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adversity ado adversities afflicts affliction afflict ailed ail agitate ails annoy anxiety annoyance annoys awkwardness bad thing bane besetment besiege bore bothers bothers bother bother break bug burdens burdens burden burden can of worms care care cares cares catastrophe check complaint complaints concern confuse confuses confusion consideration considerations corner crises crisis crunch cumber curse deep water depression depress depresses desperation deviltry devilry difficulty difficulty difficulty disagreed disagrees disagree discomfort disconcert discommode discourage discourages disoblige disorder disquiet disquiet dissension dissatisfaction distract distracts disturb distresses distresses distresses distress distress distress disturbs division dogging dog downsides downside drag drawback drawbacks dumps duties duty efforts effort embrangle embranglement embroil exertion exercise extremity extremities force fracas fret friction gall gnaw grievances grievance grief grind harass harassment hardships hardship hassle harry hates hate haunt headache hitch holdup hornet's nest hurt ill ills incommodiousness incommode incommodity interfere irk irritant jam lade load load loss mayhem matter menace millstone mindfulness mind misfortune misplacement misfortunes misfortunes mishaps misfortune/mishap molest muddle nuisance obstruction oppress pain pain pest perturb plague plagues plight predicament pressures pressure preyed on prey on problems problem put out quagmire repellency repellence repugnancy rub riots riot row ruffle scrape setback setbacks shenanigans sorrow soreness spots spot squall strains strain stressor task tasks thundercloud topsy-turviness torment torment traumatized traumatize traumatizing tries tribulation try turmoil uncertainty uncertainties unease uneasiness undoing unfortunateness unluckiness unrest unpleasantness untowardness upset unsettle visit visited visitation vexes visits vexation vex weigh down worries work woe woes worry wounds wound