| Main Entry: | |
| Part of Speech: | noun |
| Definition: | hurt condition; something that causes hurt |
| Synonyms: | adversity, anguish, calamity, cross, crux, depression, difficulty, disease, disorder, distress, grief, hardship, illness, infirmity, misery, misfortune, ordeal, pain, plague, plight, scourge, sickness, sorrow, suffering, torment, trial, tribulation, trouble, woe |
| Antonyms: | aid, comfort, consolation, health, help, relief |
| Main Entry: | aggravation |
| Part of Speech: | noun |
| Definition: | annoyance |
| Synonyms: | affliction, aggro, bother, botheration, difficulty, distress, exasperation, hang-up, headache, irksomeness, irritation, pain, pain in the neck, pet peeve, provocation, teasing, vexation, worry |
| Main Entry: | agony |
| Part of Speech: | noun |
| Definition: | suffering, pain |
| Synonyms: | affliction, anguish, distress, dolor, misery, pangs, passion, throes, torment, torture, woe |
| Antonyms: | comfort, happiness, health, peace, success |
| Main Entry: | anguish |
| Part of Speech: | noun |
| Definition: | severe upset or pain |
| Synonyms: | affliction, agony, distress, dole, dolor, grief, heartache, heartbreak, hurting, misery, pang, rue, sorrow, suffering, throe, torment, torture, woe, wretchedness |
| Antonyms: | comfort, contentment, happiness, joy, joyfulness, solace |
| Main Entry: | bane |
| Part of Speech: | noun |
| Definition: | cause of misery |
| Synonyms: | affliction, blight, burden, bête noir, calamity, curse, despair, destruction, disaster, downfall, fatal attraction, misery, nuisance, pest, plague, poison, ruin, ruination, scourge, torment, trial, trouble, undoing, venom, woe |
| Antonyms: | advantage, blessing, fortune, good luck |
| Main Entry: | bereavement |
| Part of Speech: | noun |
| Definition: | death; loss |
| Synonyms: | affliction, deprivation, distress, misfortune, sorrow, tribulation |
| Main Entry: | blight |
| Part of Speech: | noun |
| Definition: | disease; plague |
| Synonyms: | affliction, bane, blot on the landscape, canker, contamination, corruption, curse, decay, dump, evil, eyesore, fungus, infestation, mildew, pest, pestilence, pollution, rot, scourge, sight, withering, woe |
| Antonyms: | blessing, boon, health, prosperity |
| Main Entry: | blow |
| Part of Speech: | noun |
| Definition: | catastrophe |
| Synonyms: | affliction, balk, bolt from the blue, bombshell, calamity, casualty, chagrin, comedown, debacle, disappointment, disaster, disgruntlement, frustration, jolt, letdown, misadventure, misfortune, mishap, reverse, setback, shock, tragedy, upset |
| Antonyms: | good fortune, luck |
| Main Entry: | burden |
| Part of Speech: | noun |
| Definition: | mental weight; stress |
| Synonyms: | Herculean task, accountability, affliction, albatross, anxiety, ball and chain, blame, care, charge, clog, concern, deadweight, difficulty, duty, encumbrance, excess baggage, grievance, hardship, hindrance, load, millstone, misfortune, mishap, obstruction, onus, punishment, responsibility, sorrow, strain, task, tax, thorn in one's side, trial, trouble, weary load, work, worry |
| Antonyms: | aid, help, relief |