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Definitions

pain

[peyn] / peɪn /
NOUN
physical suffering
Synonyms
STRONGEST
ache agony burn cramp discomfort fever illness injury irritation misery sickness soreness spasm strain tenderness torment trouble twinge wound
STRONG
affliction catch convulsion crick distress gripe hurt laceration malady pang paroxysm prick smarting sting stitch throb throe tingle torture
Antonyms
STRONGEST
advantage aid assistance benefit blessing comfort contentment ease good health happiness health help joy peace pleasure relief wellness
WEAK
cheer well-being
NOUN
mental suffering
Synonyms
STRONGEST
agony anguish anxiety bitterness grief heartache misery sadness shock suffering torment woe worry
STRONG
affliction despondency distress hurt malaise martyrdom rack torture travail tribulation wretchedness
Antonyms
STRONGEST
calmness cheer comfort contentment delight gladness happiness health joy peace
STRONG
aid help relief
WEAK
good health irritation pleasure well-being
NOUN
problem
Synonyms
STRONGEST
irritation trouble
STRONG
aggravation annoyance bore bother drag effort exertion nuisance pest vexation
Antonyms
STRONG
delight happiness idleness laziness pleasure
WEAK
cheer comfort good health health joy well-being
VERB
bother, trouble
Synonyms
STRONG
ache afflict aggrieve agonize ail anguish annoy bite chafe chasten constrain convulse discomfort disquiet distress exasperate excruciate gall grieve gripe harass harm harrow hurt inflame injure irk irritate nick prick punish rack rile sadden smart sting strain stress suffer throb tingle torment torture upset vex worry wound
WEAK
cut to the quick hit where one lives
Antonyms
STRONG
aid alleviate appease assist assuage calm cheer comfort cure delight ease encourage fix heal help let go make happy mend placate please praise relieve soothe

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

"We were initially studying TRPV4 in the context of pain," Gualdani explained.

From Science Daily • May 10, 2026

Researchers noted that the music allowed exercisers to remain in what they described as the "pain zone" longer without increasing how difficult the effort felt.

From Science Daily • May 9, 2026

"It is a howl of pain," said one minister, reflecting that so many people in the Labour Party this weekend are hurting.

From BBC • May 9, 2026

She dies confused, in pain, not ready to go, as am I, confused, in pain, and not ready to let her go.

From Salon • May 9, 2026

At last it was free of the terrible pain that had stilled its roar and quenched its fire for so many days.

From "Rowan of Rin" by Emily Rodda

Vocabulary lists containing pain

Selection Vocabulary 1, Unit 4

Looking to grow your vocabulary? Check out this interactive, curated word list from our team of English language specialists at Vocabulary.com – one of over 17,000 lists we've built to help learners worldwide!