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ado adversity adversities afflict afflicts affliction agitate ails ail ailed annoy annoys annoyance anxiety awkwardness bad thing bane besetment besiege bothers bothers bother bother bore break bug burden burden burdens burdens can of worms care care cares cares catastrophe check concern confusion confuses consideration complaint complaints confuse considerations corner crisis crises crunch cumber curse deep water depress depresses desperation depression deviltry devilry difficulty difficulty difficulty disagrees disagreed disagree disconcert discomfort discommode discourage discourages disorder disoblige dissension disquiet disquiet dissatisfaction distract distresses distresses distresses distress distress distress distracts disturbs disturb division dogging dog downsides downside drag drawback drawbacks dumps duty duties efforts embrangle effort embranglement embroil exertion exercise extremities extremity force fracas fret friction gall gnaw grief grievances grievance grind hardships harass harry harassment hates hardship hassle hate headache haunt hitch holdup hornet's nest hurt ill ills incommode incommodity incommodiousness interfere irk irritant jam lade load load loss mayhem matter menace millstone mind mindfulness misfortunes misfortunes misfortune misplacement mishaps misfortune/mishap molest muddle nuisance obstruction oppress pain pain pest perturb plagues plague plight predicament pressures pressure preyed on prey on problem problems put out quagmire repellency repellence repugnancy riots riot row rub ruffle scrape setback setbacks shenanigans soreness sorrow spot spots squall strain strains stressor tasks task thundercloud topsy-turviness torment torment traumatized traumatizing tribulation traumatize tries try turmoil uncertainty uncertainties undoing uneasiness unease unluckiness unfortunateness untowardness unpleasantness unrest upset unsettle vexation vexes visitation visits vex visit visited weigh down woe woes work worries wound worry wounds