| Main Entry: | |
| Part of Speech: | noun |
| Definition: | ache, twinge |
| Synonyms: | agony, anguish, bite, discomfort, distress, gripe, misery, pain, prick, spasm, stab, sting, stitch, throb, throe, wrench |
| Antonyms: | tingle |
| Main Entry: | agony |
| Part of Speech: | noun |
| Definition: | suffering, pain |
| Synonyms: | affliction, anguish, distress, dolor, misery, pangs, passion, throes, torment, torture, woe |
| Antonyms: | comfort, happiness, health, peace, success |
| Main Entry: | anguish |
| Part of Speech: | noun |
| Definition: | severe upset or pain |
| Synonyms: | affliction, agony, distress, dole, dolor, grief, heartache, heartbreak, hurting, misery, pang, rue, sorrow, suffering, throe, torment, torture, woe, wretchedness |
| Antonyms: | comfort, contentment, happiness, joy, joyfulness, solace |
| Main Entry: | cramp |
| Part of Speech: | noun |
| Definition: | muscle spasm |
| Synonyms: | ache, charley horse, circumscription, confinement, constipation, contraction, convulsion, crick, hindrance, impediment, kink, obstruction, pain, pang, restriction, shooting pain, stiffness, stitch, stricture, twinge |
| Main Entry: | desperation |
| Part of Speech: | noun |
| Definition: | hopelessness |
| Synonyms: | agony, anguish, anxiety, concern, dejection, depression, desolation, despair, despondency, discomfort, disconsolateness, distraction, distress, fear, gloom, grief, heartache, melancholy, misery, pain, pang, sorrow, torture, trouble, unhappiness, worry |
| Antonyms: | confidence, contentment, security |
| Main Entry: | distress |
| Part of Speech: | noun |
| Definition: | pain, agony |
| Synonyms: | ache, affliction, anguish, anxiety, bad news, blues, care, concern, cross, dejection, desolation, disappointment, discomfort, disquietude, dolor, embarrassment, grief, headache, heartache, heartbreak, irritation, malaise, misery, mortification, ordeal, pang, perplexity, sadness, shame, sorrow, stew, suffering, throe, torment, torture, trial, tribulation, trouble, twinge, unconsolability, unhappiness, vexation, visitation, woe, worriment, worry, wretchedness |
| Antonyms: | comfort, happiness, health, pleasure |
| Main Entry: | gripe |
| Part of Speech: | noun |
| Definition: | complaint |
| Synonyms: | ache, aching, affliction, disorder, distress, grievance, groan, grouse, grumble, illness, indisposition, infirmity, moan, objection, pain, pang |
| Antonyms: | compliment, flattery, praise |
| Main Entry: | heartache |
| Part of Speech: | noun |
| Definition: | anguish, sorrow |
| Synonyms: | affliction, agony, bitterness, broken heart, dejection, depression, despair, despondency, distress, dolor, grief, heartbreak, heavy heart, hurting, misery, pang, remorse, sadness, suffering, torment, torture |
| Main Entry: | hurt |
| Part of Speech: | noun |
| Definition: | injury; damage |
| Synonyms: | ache, black and blue, blow, boo-boo, bruise, chop, detriment, disadvantage, disaster, discomfort, disservice, distress, down, gash, harm, ill, ill-treatment, loss, mark, mischief, misfortune, nick, ouch, outrage, pain, pang, persecution, prejudice, ruin, scratch, sore, soreness, suffering, wound, wrong |
| Antonyms: | aid, assist, cure, healing, help, remedy |