efflux

Nedergaard proposed that this efflux relied on the pumping of fluid through tiny glymphatic vessels between neurons, which her team had identified in an earlier study.

But he questioned whether the influx of dye was a reliable proxy for efflux, which he says would be impossible to measure directly by tracking every blood or lymphatic vessel or potential exit point from the brain.

But it will also rise if the hole at the bottom shrinks—if efflux slows.

To address this, the scientists designed new versions of the drug spectinomycin that overcome efflux, the main mechanism driving resistance.

The N-ethylene linkage structure of the eAmSPCs plays a critical role in how the compounds avoid efflux, suggesting that longer linkages modify how the compound is pumped out of the cell.