tightly

Depending on chemical markers placed on these histones, the chromatin can be wound tightly -- preventing transcription factors from binding -- or loosely, making it accessible for generating mRNA copies.

As well as restricting social media for young people, some suggest their use of smartphones should also be more tightly controlled.

Instead, the pieces are carefully cut to fit together tightly.

The Brazilian government believes the January 2023 riots were part of a coup attempt orchestrated by Bolsonaro following his defeat in a tightly contested presidential election the previous October.

And while experiments with animals in labs can be tightly controlled, the results may be skewed since the animal is not interacting within its natural environment.