run up against

But if Kennedy hopes to target junk food, he will first have to shake up the country's food regulations - and run up against Big Food.

Although the play, directed by Simon Levy, is set in Britain, anyone from the U.S. who has run up against our own healthcare bureaucracy should be able to relate.

Here though they would run up against Google's incredibly strong customer recognition for search.

Even leading experts in vaccine science have run up against disbelief and ambivalence.

But in doing so they have run up against two bigger mysteries, including one that casts doubt on where our heavy elements - like gold - come from.