regulator gene

The last two columns indicate whether a given gene is member of the DDR and/or the cell cycle regulator gene set.

"This is the first major study that shows how small changes in one master regulator gene can cause a cascade of other metabolic effects in other genes," said lead author Tim Spector in a statement.

Researchers are also studying the usefulness of a test to detect the fusion of two genes—a precursor regulator gene called TMPRSS2 and a cancer-causing gene known as ERG.