refractory

As our patient battled drug toxicities and refractory infection, we began to discuss one last option.

Diagnosed with refractory acute myeloid leukemia at age 7, Sam was very brave but also very sick.

When pure and of close hard grain it is used as a refractory for lining furnaces, especially those designed for anthracite.

And so mother and daughter in Mr. Wilding's absence pleaded his cause with his refractory bride-elect.

At last one of the men mounted his horse, and set out with his lariat to lasso the refractory beast in true cow-boy style.

The guard-room, 8, is identified by the remains of stocks, in which the refractory were fastened for punishment or safe-keeping.

She understood literature and the beauties of poetry, but it was too late to cultivate her refractory memory.