papule

The first appearance is that of a sharply defined papule, rarely larger than a split pea.

Involution is marked by cessation of oozing, subsidence of the papule and scar-like changes at the site of the lesion.

Ordinarily, no effect whatever is observed until after the lapse of two or three days, when a red papule is formed.

This papule increases in superficial area, but not in height, and gradually loses its redness.

The vesicles are superficial in situation, the firm papule which precedes the variolous rash being altogether wanting.