most significant

The proposals would likely be the most significant remedies to be requested in a tech antitrust case since the Justice Department asked to break up Microsoft in 2000.

“Federal law requires the Colorado River Basin’s reservoirs be managed in accordance with the Colorado River Compact — the most significant component of which is mandatory deliveries of water from the Upper Basin to the Lower Basin and Mexico,” said J.B.

The truth is, of course, that in the most significant expansion of the program, under the ACA, 100% of the cost of covering the new enrollees was borne by the federal government from 2016 through 2018, gradually declining to 90% in 2020 and thereafter.

Russia's main offensive has long focused on the eastern Donetsk region, but this was one of the most significant ground assaults since the start of the war and further stretched Ukraine's front-line defences.

Warmer ocean temperatures in the tropical Pacific from late 2014 into 2016, culminating in one of the most significant El Niño events since 1950, led to shifts in atmospheric jet streams that altered weather and rainfall patterns around the world.