in the first place

One of the most effective ways of doing this is to develop antibodies that bind to the protein and block it from being nitrated in the first place.

That's if he ever cared about the noise in the first place, which is doubtful.

Von Meyenn adds: "It's precisely because of this memory effect that it's so important to avoid being overweight in the first place. Because that's the simplest way to combat the yo-yo phenomenon."

Politicians had to "stop insulting your intelligence with the chicanery of easy answers, when that is exactly how we got into this mess in the first place", he said.

The decision to hire Juric in the first place only served to highlight the lack of a clear sporting strategy.