debilitate

But endometriosis and adenomyosis have left her housebound, in debilitating pain, and unable to see a future as a mum.

"By blocking these endocannabinoid receptors just on these specific interneurons, we could essentially prevent one of the most debilitating symptoms of PTSD."

To witness them supporting one another musically and showing inspiring devotion to a frail Barenboim, suffering from a debilitating neurological disease, may be the only gleam of hope we have for peace.

The U.N. warned in a recent report that without greater action to stop emissions, the world could see as much as 5.6 degrees of warming by 2100, bringing “debilitating impacts to people, planet and economies.”

As a teenager, Edim effectively became a single parent not only to her brothers but also to her mother, whose divorce from her second husband sent her into a debilitating depression.