carefully

And the researchers stress their study, published in Annals of Neurology, used carefully controlled prescription medication.

For the model, a subset of these variables was carefully selected using a combination of data-driven methods and clinician input, gathered through a survey of expert pediatric neurosurgeons nationwide.

"Our team started spiking a range of carefully selected small molecules to the plasma with the aim of minimizing the interactions of highly abundant proteins with nanoparticles," Mahmoudi said.

When a blizzard hits the town and leaves the parents separated from the children, their carefully planned celebrations are thrown into chaos.

"The BBC has robust safeguarding policies and processes in place and if people contact us directly with concerns we will look at these carefully, in line with our complaints framework," they added.