ventral

The proliferation was isolated to a brain region known as the ventral tegmental area, which is involved in reward learning and addiction.

When researchers repeated the drug injections or brain stimulation for several days, then examined the mice a month later, they indeed found more oligodendrocytes and more myelinated dopamine-producing cells, with thicker myelin around their axons, again only in the ventral tegmental area.

Five years later, Du is now an undergraduate at Duke University, and the method she helped develop has been used to predict neurotransmitters in connectomes of the fruit fly hemibrain, ventral nerve cord, and optic lobe created by Janelia researchers and collaborators, as well as the adult fly brain connectome created by FlyWire.

Dr. Edlow explains, "Our connectivity results suggest that stimulation of the ventral tegmental area's dopaminergic pathways has the potential to help patients recover from coma because this hub node is connected to many regions of the brain that are critical to consciousness."

The researchers also found a neuronal abnormality in the developing brains of these offspring, specifically in the ventral hippocampus, a region that has been linked to anxiety and anxious behavior.