perforation

They showed that the previously accepted idea that azoles kill the pathogen cell by causing perforation of the outer cell membrane does not apply.

Abiomed first disclosed the risk of heart perforation during insertion of the pumps in a technical bulletin posted in October 2021, but did not share this information with the FDA at the time, the agency said.

The agency carried out an inspection of the firm's office in Massachusetts in early 2023, and sent a warning letter to Abiomed in September where it criticised - among other things - a failure to update the FDA on the risk of heart perforation.

The F.D.A. said the manufacturer of the device, Abiomed, should have notified the agency more than two years ago, when the company first posted an update on its website about the perforation risk.

And it is only when she is grown, and a prize-winning poet, that she found the right word to describe what the IRA bullets inflicted on her dad's body: Perforation.