significant
Usage
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
"Our results suggest that altered metabolism is a significant contributor to Alzheimer's progression and, in addition, addressing the metabolic defect could be an important complement to approaches focused on Alzheimer's plaques and tangles," Sun said.
From Science Daily • Jun. 10, 2026
The island also contains many culturally significant sites for the Chumash people.
From Los Angeles Times • Jun. 10, 2026
This at least is a possible reason for Epstein wanting to know someone like Gates - who, while not a politician, is a global figure with significant networks and influence.
From BBC • Jun. 10, 2026
The company said it doesn’t expect to book any significant cost from the termination of the study, and that its guidance for 2026 remains unchanged.
From The Wall Street Journal • Jun. 10, 2026
Virchow made significant discoveries in oncology—the treatment of tumors—and parasitology, the scientific study of parasites.
From "Mountains Beyond Mountains" by Tracy Kidder and Michael French
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Vocabulary lists containing significant
Academic Vocabulary: Core Tier 2 Words, List 1
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The SAT: Language of the Test, List 6
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The Language of Standardized Tests, List 4
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