profound

Many people struggle with loneliness and lack of purpose when they leave their jobs, and the effects can be profound.

From MarketWatch ● Nov. 7, 2026

“Representing San Francisco is an extraordinary honor and a profound responsibility. My office stands ready to assist in the transition, and I wish him success in service for the people of our city,” she said.

From Los Angeles Times ● Nov. 5, 2026

In a statement, the LMB paid tribute to the "inspiring, talented and passionate scientist" and described her death as a "profound shock and a huge loss".

From BBC ● Nov. 3, 2026

He left a profound mark on the Andean nation, which adopted him as one of its own.

From Barron's ● Nov. 3, 2026

Jack nodded, looking from Phillip to May, and suddenly he felt the need to say something profound.

From "Half Upon a Time" by James Riley

The sensitive percussionist Steven Schick played the opening shimmer of bells with even profounder quiet, and there were more flickers in Kashkashian’s tone.

From New York Times ● Feb. 21, 2022

It also results in the profounder album of the two.

From Washington Times ● Apr. 4, 2018

It isn't elitist to think that Four Quartets is chewier, profounder and more artful than If or The Song of Hiawatha: it is simply common sense.

From The Guardian ● Apr. 10, 2011

Or, as Frank notes while dealing with a particularly difficult couple in Independence Day, “a profounder text runs beneath all realty decisions.”

From Newsweek

In no other writer, ancient or modern, will he find a profounder sense of human dignity, of the supreme claims of affection, of the superiority of a natural to a conventional life.

From The Roman Poets of the Republic by W. Y. Sellar

He quotes Nietzsche saying, “The profoundest mind must also be the most frivolous one.”

From New York Times ● Apr. 27, 2022

Photography’s profoundest limitation is its mechanistic nature, which can bind it to a literalness and a brittle understanding of time.

From Washington Post ● Apr. 20, 2021

David Bowman would turn out to one of the most isolated people I’ve ever known—isolated on the profoundest levels by a certain traumatic displacement from ordinary human consolation.

From The New Yorker ● Jan. 2, 2019

That might sound painfully earnest, but the Greeks understood that our profoundest pleasures aren’t superficial.

From Los Angeles Times ● Dec. 26, 2017

I watched with the profoundest satisfaction as five days of grime ran down my legs and out the drainhole, and noticed with astonished gratitude that my body had taken on a noticeably svelter profile.

From "A Walk in the Woods" by Bill Bryson