| Main Entry: | |
| Part of Speech: | noun |
| Definition: | upset, provocation |
| Synonyms: | aggravation, anger, annoyance, besetment, bother, botheration, displeasure, exacerbation, fury, ire, irritant, irritation, nuisance, passion, pest, pique, plague, rage, resentment, vexation, wrath |
| Antonyms: | calming, calmness, comfort, ease, placation, pleasing, soothing |
| Main Entry: | frustration |
| Part of Speech: | noun |
| Definition: | disappointment, thwarting |
| Synonyms: | annoyance, bitter pill, blocking, blow, bummer, chagrin, circumvention, contravention, curbing, defeat, disgruntlement, dissatisfaction, downer, drag*, failure, fizzle, foiling, grievance, hindrance, impediment, irritation, letdown, nonfulfillment, nonsuccess, obstruction, old one-two, resentment, setback, unfulfillment, vexation |
| Antonyms: | aid, assistance, cooperation, encouragement, facilitation, help, support |
| Main Entry: | goad |
| Part of Speech: | noun |
| Definition: | stimulus |
| Synonyms: | catalyst, compulsion, desire, drive, impetus, impulse, impulsion, incentive, incitation, incitement, irritation, lash, lust, motivation, passion, pressure, prod, spur, urge, whip, zeal |
| Antonyms: | deterrent, discouragement, diversion, restraint |
| Main Entry: | harassment |
| Part of Speech: | noun |
| Definition: | badgering |
| Synonyms: | aggravation, annoyance, bedevilment, bother, bothering, disturbance, exasperation, hassle, irking, irritation, molestation, nuisance, persecution, perturbation, pestering, provocation, provoking, torment, trouble, vexation, vexing |
| Antonyms: | aid, assistance, facilitation, furtherance, help, support |
| Main Entry: | inflammation |
| Part of Speech: | noun |
| Definition: | redness, swelling |
| Synonyms: | burning, infection, irritation, pain, rash, sore, tenderness |
| Main Entry: | itch |
| Part of Speech: | noun |
| Definition: | scratching; tingling |
| Synonyms: | crawling, creeping, irritation, itchiness, prickling, psoriasis, rawness, tickle |
| Main Entry: | nerves |
| Part of Speech: | noun |
| Definition: | extreme anxiety |
| Synonyms: | fretfulness, hysteria, imbalance, irritation, nervousness, neurasthenia, sleeplessness, strain, stress, tenseness, tension |
| Antonyms: | calm, coolness |
| Main Entry: | nuisance |
| Part of Speech: | noun |
| Definition: | annoyance; annoying person |
| Synonyms: | besetment, blister, bore, bother, botheration, botherment, bum*, creep, drag*, drip*, exasperation, frump, gadfly, headache, inconvenience, infliction, insect*, irritant, irritation, louse, nag*, nudge*, offense, pain, pain in the neck, pest, pester, pesterer, pill, plague, poor excuse, problem, terror, trouble, vexation |
| Antonyms: | delight, happiness, pleasantry, pleasure |
| Main Entry: | pain |
| Part of Speech: | noun |
| Definition: | physical suffering |
| Synonyms: | ache, affliction, agony, burn, catch, convulsion, cramp, crick, discomfort, distress, fever, gripe, hurt, illness, injury, irritation, laceration, malady, misery, pang, paroxysm, prick, sickness, smarting, soreness, spasm, sting, stitch, strain, tenderness, throb, throe, tingle, torment, torture, trouble, twinge, wound |
| Notes: | a pain is something that hurts; an ache is a prolonged dull pain a pain is something that hurts as a consequence of injury, disease, or emotional disorder; a pane is a sheet glass cut in shapes for windows or doors |
| Antonyms: | comfort, good health, health, well-being |