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Definitions

extreme

[ik-streem] / ɪkˈstrim /






Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Soleno, which develops treatments of rare diseases, is known for its Vykat XR drug to treat the extreme hunger caused by rare genetic disorder Prader-Willi syndrome.

From The Wall Street Journal • Apr. 6, 2026

More extreme cases can end up with prosecutors.

From MarketWatch • Apr. 6, 2026

The acquisition grants Neurocrine access to Vykat XR, a drug approved in March 2025 for extreme hunger in Prader-Willi syndrome patients.

From Barron's • Apr. 6, 2026

Despite this large size, the layer maintained a thickness of just 40 nanometers, giving it an extreme aspect ratio.

From Science Daily • Apr. 5, 2026

His extreme close-up unibrow glares out at me, looking like it’s been crammed into a too-small jam jar.

From "Linked" by Gordon Korman