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Definitions

extreme

[ik-streem] / ɪkˈstrim /






Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Soleno, which develops treatments of rare diseases, is known for its Vykat XR drug to treat the extreme hunger caused by rare genetic disorder Prader-Willi syndrome.

From The Wall Street Journal • Apr. 6, 2026

“This is an extreme outcome” in the absence of a recession or interest-rate hikes by the Federal Reserve, said Wilson.

From MarketWatch • Apr. 6, 2026

The acquisition grants Neurocrine access to Vykat XR, a drug approved in March 2025 for extreme hunger in Prader-Willi syndrome patients.

From Barron's • Apr. 6, 2026

Despite this large size, the layer maintained a thickness of just 40 nanometers, giving it an extreme aspect ratio.

From Science Daily • Apr. 5, 2026

St. Sebastian had been named the patron saint of athletes and soldiers, because he’d been forced to endure extreme physical trials in his life but was able to heal quickly from his injuries.

From "Courage to Soar" by Simone Biles