ideal

In an "ideal world" the rebrand leads to buzz and a positive reaction, Mr Rolston adds, but to achieve that you need to "make sure people understand the context".

Hardly ideal when Wales have lost a record 11 consecutive internationals, Gatland's side are facing an 11th defeat in a so far winless calendar year when they have slipped to 11th in the world.

Just as a chef perfects a dish by experimenting with flavors and textures, the researchers used an iterative process, testing variations to find the ideal structure for the ionizable lipid.

For example, colorectal cancer, which has multiple treatment options but poor outcomes in the late stages, is an ideal candidate for clinical trials of this approach.

Congressional leaders from both parties agree on the need to pass PBM reform, and the current "lame duck" legislative session is an ideal opportunity to do so.