grand climacteric

He had been dropping hints, in truth, throughout his second term, describing himself as “on the advanced side of the grand climacteric” and too old for the rigors of the job, repeating his familiar refrain about the welcome solace of splendid isolation beneath his “vine and fig tree” at Mount Vernon.

It was my ill-fortune, however, to be equally unknown to all three leaders, and as the month of December which saw me thus miserably straitened saw me reach the age of forty, which I regard, differing in that from many, as the grand climacteric of a man's life, it will be believed that I had need of all the courage which religion and a campaigner's life could supply.

But perhaps it is a grand climacteric and will pass away.

It has indeed "all been before, this sort of thing"; only when an extremely clever person, whose friends have always been saying, with an exclamation rather than an interrogation point appended, "Why don't you write a novel!" ... waits until he has passed his grand climacteric, he displays more faith in Providence than in himself.

Sir Thomas Browne, who loved miracles, did not hesitate to classify the supposed importance of the grand climacteric as a vulgar error; he included a whole quaint chapter on the subject, in that old curiosity shop of literature, the Pseudodoxia Epidemica.