substance

The 69-year-old Oscar winner and "Gladiator II" star reflected on his relationship with alcohol and substances in an interview with Esquire.

"There are EU regulations around the use of lead, but piezoelectrics are one of the last remaining mainstream technologies allowed to contain this substance because there is no high-performance alternative," Associate Professor Guerin explained.

He and Brynn, who battled substance abuse, had a tumultuous, combative relationship that was growing only more strained.

"Normally, microglia are looking for things like viruses or injury and secreting substances that block off the damage," she said.

In more extreme cases, Professor Gillan's research has shown that it can even contribute to compulsive behaviours seen in conditions such as obsessive compulsivedisorder, substance use disorders, and eating disorders.