irreversible

The show played a barrage of congressional Democrats comparing Trump to Adolf Hitler, stressing he is "a threat to Democracy" who could cause "irreversible" damage to the country.

“The science on climate change is unforgiving, with every year of delay locking in more costs and more irreversible changes, and everyday people paying the steepest price.”

Last year Unesco said the city should be added to a list of world heritage sites in danger, as the impact of climate change and mass tourism threaten to cause irreversible changes to it.

The 2023 law, however, bans abortions after six weeks only when they’re “necessary to save the pregnant woman’s life or avert a serious risk of ... irreversible physical impairment” of the pregnant woman.

There is no cure for the disease, and paralysis caused by an infection is irreversible.