downside

Carsley will start work on his report to Tuchel presumably after a rest, and admitted he harbours one major downside from his time in charge.

The downside is that their limited lifespan results in vast numbers of spent LIBs that contain dangerous heavy metals and other hazardous materials.

However, the downside is that a complete blockade of this "editing office" also affects healthy cells, resulting in significant side effects of any spliceosome inhibitor developed so far.

And while incompetence is better than competence in his appointees, there are downsides.

While it may feel better to think of Trump supporters as misinformed rather than hateful, the downside is that an un-informed public cannot sustain a freely elected democracy.