vitiation

That is to say, a vitiation of taste, by indulged excesses; the wine and high feasting of their own theatre—which really made them unapt for understanding Shakspeare.

From Blackwood's Edinburgh Magazine, Volume 57, No. 353, March 1845 by Various

They are usually accompanied with a well-developed fetus, so that the mole may be looked upon as a twin which has undergone arrest and vitiation of development.

From Special Report on Diseases of the Horse by Charles B. Michener

Perhaps this is a vitiation due to that malady of mankind called civilization; but a woman in squalid poverty would exert no fascination over me, were she attractive as Homer's Galatea, the fair Helen.

From The Magic Skin by Ellen Marriage

Like most of the papers on which we subsequently worked together, the object was not merely to amuse, but also to strike at some prevailing literary craze or vitiation of taste. 

From The Bon Gaultier Ballads by Richard Doyle

Next, in regard to vitiation of the air, by which is meant the alteration in its composition resulting from the admixture of products of combustion with it.

From Acetylene, the Principles of Its Generation and Use A Practical Handbook on the Production, Purification, and Subsequent Treatment of Acetylene for the Development of Light, Heat, and Power by F. H. (Frank Henley) Leeds