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Definitions

lou

[loo] / lu /
ADJECTIVE
horrid
Synonyms
STRONGEST
abominable appalling awful disgusting dreadful frightful ghastly grim grisly gruesome hideous horrific
WEAK
abhorrent beastly bloodcurdling cruel detestable disagreeable eerie execrable fearful gross hair-raising heinous loathsome
Antonyms
STRONGEST
attractive beautiful delightful nice pleasant pleasing pretty wonderful

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Increased levels of klotho are thought to combat inflammation and improve cognition, and therapies to boost its production are being developed in the U.S. to target specific neurodegenerative ailments, such as Lou Gehrig’s disease.

From Slate • Mar. 30, 2026

Three-year-old Agatha Acker, in a cute gingham outfit and gas mask, brought along her doll, Betty Lou, also tricked out in a pretty dress, and a gas mask.

From Los Angeles Times • Mar. 26, 2026

Rui Cardoso, a portfolio manager at Beutel Goodman, recommends Japan’s Shionogi, a pharmaceutical company that is developing drugs for depression and ALS, more commonly known as Lou Gehrig’s disease.

From Barron's • Mar. 19, 2026

NPC spokesman Lou Qinjian said there were plans to be implemented to achieve this in the future.

From BBC • Mar. 11, 2026

Mary Lou put her hand on his arm.

From "Jeremy Thatcher, Dragon Hatcher" by Bruce Coville

From Roget's 21st Century Thesaurus, Third Edition Copyright © 2013 by the Philip Lief Group.