challenge
Example Sentences
Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.
One challenge in vaccine development is that immune responses in mice often do not fully reflect what happens in humans.
From Science Daily
“We urge the university to defend itself, and defend our community, by challenging the factual and legal bases” of the suit, the professors said.
From Los Angeles Times
When her anxiety about her finances flares up, she draws strength from how women have historically risen to the occasion when faced with challenges, she said.
From Salon
The ruling said: "Martinelli is not looking at the ball, holds Weiffer into the area and prevents the Brighton player from challenging for the ball."
From BBC
It was a stark reminder of the challenges the more militant edge of the Ultra movement poses.
From BBC
From Roget's 21st Century Thesaurus, Third Edition Copyright © 2013 by the Philip Lief Group.