challenge

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

However, it creates a challenge in cancer therapy because many treatments work by damaging tumor DNA beyond repair.

From Science Daily • May 17, 2026

Although Carano is unlikely to pose a competitive challenge for Rousey, both women are approaching the event more as pioneers than as rivals.

From Los Angeles Times • May 16, 2026

But current Carlsbad officials have sided with Levy—and have hired outside counsel to challenge the commission’s claims.

From The Wall Street Journal • May 16, 2026

Large-scale transport of medical equipment is a challenge in DR Congo, a country of more than 100 million people which is four times the size of France but has poor communications infrastructure.

From Barron's • May 16, 2026

Teller stayed at Los Alamos and aimed his relentless brain at the challenge of the Super.

From "Fallout: Spies, Superbombs, and the Ultimate Cold War Showdown" by Steve Sheinkin