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refractory

[ri-frak-tuh-ree] / rɪˈfræk tə ri /


ADJECTIVE
inflexible
Synonyms
Antonyms


Example Sentences

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Late-phase data for the U.K. drugmaker’s camlipixant and bepirovirsen in refractory chronic cough and hepatitis B, respectively, are due and the outcome of a portfolio review should come alongside second-quarter results, the analysts say.

From The Wall Street Journal May 5, 2026

The Food and Drug Administration has accepted a biologics license application for anito-cel as a fourth-line treatment for patients with relapsed or refractory multiple myeloma.

From Barron's Feb. 23, 2026

This refractory metal-based material, in whose discovery Dr. Alexander Kauffmann, now professor at the Ruhr University Bochum, played a major role, exhibits properties never seen before.

From Science Daily Oct. 23, 2025

He said the medical cause of Benn's death was "refractory cardiogenic shock due to taxane alkaloid poisoning, following ingestion of yew tree berries and leaves".

From BBC Dec. 4, 2023

So Meg wrestled alone with the refractory sweetmeats all that hot summer day, and at five o’clock sat down in her topsy-turvey kitchen, wrung her bedaubed hands, lifted up her voice and wept.

From "Little Women" by Louisa May Alcott

U.S. and European companies have been recently investing in developing synthetic graphite as demand from the EV sector is surging for this soft form of carbon, which until recently was mainly used for steelmaking refractories.

From Reuters Oct. 20, 2023

It boasted that it was the world's No. 1 producer of aluminum, tinplate, refractories, plumbing fixtures, lifting jacks, air brakes.

From Time Magazine Archive

To insure tranquillity at the West, now full of refractories, Napoleon believed it necessary to inspire terror.

From The Brotherhood of Consolation by Katharine Prescott Wormeley

The Vice-palatine's task was to teach these refractories, through patriotic reasoning, to amend their ways.

From The Nameless Castle by Mór Jókai

On arriving at Saint-Savin, the women Lechantre and Bryond heard of the arrest of Bourget, that of the driver of the diligence, and that of the two refractories.

From The Brotherhood of Consolation by Katharine Prescott Wormeley




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