irreversible

This approach provides you with flexibility to evaluate your circumstances every year, and also “avoids making a large, irreversible tax decision based on a single year’s circumstances.”

From MarketWatch ● Sep. 2, 2026

But the National Trust for Historic Preservation argued that construction was causing irreversible damage to a historical landmark.

From BBC ● Aug. 31, 2026

Instead, chromosome changes tend to move along a restricted set of irreversible pathways that the researchers describe as "evolutionary highways."

From Science Daily ● Aug. 25, 2026

But Pyongyang has rejected his overtures, labelling Seoul its "most hostile" enemy and declaring itself an "irreversible" nuclear state.

From Barron's ● Aug. 18, 2026

That one temporary decision became irreversible, because no shipyards remained to turn out ships that would prove the folly of that temporary decision, and to serve as a focus for rebuilding other shipyards.

From "Guns, Germs, and Steel: The Fates of Human Societies" by Jared M. Diamond