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The discovery, published in iScience, shows that restoring the balance of neuronal excitability within a precise part of the amygdala can reverse these behavioral changes in mice.

To confirm their findings, the scientists compared mouse models of Crohn's disease that lacked the girdin protein with those that still had it.

A team of researchers at Washington University School of Medicine in St. Louis has now demonstrated, in mouse models, that Alzheimer's disease disrupts circadian rhythms within specific brain cells.

Using genetically engineered mice that develop Progeria, the researchers observed early heart problems similar to those found in children with the disease.

The study, published in Nature Aging, explored how changes in the circadian system affect brain health and memory in mouse models of Alzheimer's disease.