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Definitions

degenerative

[dih-jen-er-uh-tiv, -uh-rey-tiv] / dɪˈdʒɛn ər ə tɪv, -əˌreɪ tɪv /


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

CTE is a degenerative brain disease that has been found in people exposed to repetitive head trauma; it can be diagnosed only after death.

From Los Angeles Times • Apr. 7, 2026

Petrou was diagnosed with retinitis pigmentosa, a degenerative disorder that leads to vision loss, at age 18.

From The Wall Street Journal • Mar. 12, 2026

The researchers say these findings challenge the routine practice of recommending exercise as the first line treatment for reducing pain and improving mobility in people with this degenerative joint disease.

From Science Daily • Feb. 25, 2026

That diagnosis was subsequently changed to one of progressive supranuclear palsy, a degenerative brain disease with similar symptoms.

From BBC • Feb. 17, 2026

Katie leaned forward, and I whispered the many problems I’d been suffering, which had led to the diagnosis of chronic, degenerative, relapsing-remitting inflammobetigoitis.

From "Liar, Liar" by Gary Paulsen