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Definitions

insoluble

[in-sol-yuh-buhl] / ɪnˈsɒl yə bəl /


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

In the mouse model, oral arginine lowered amyloid plaque formation and reduced insoluble Aβ42 levels in the brain.

From Science Daily • Nov. 21, 2025

It’s the counterpoint to Syd’s earliest argument for sticking with this insoluble endeavor: “Why can’t we put everything that we have into everything that we can?”

From Salon • Jun. 26, 2025

But if a problem is insoluble, it’s not a problem anymore; it’s just the way things are.

From Salon • Dec. 31, 2024

Buck researchers have recently completed a systematic study in worms that paints an intricate picture of the connections between insoluble proteins in neurodegenerative diseases and aging.

From Science Daily • May 16, 2024

More than the question of compensation, then, the relocation problem was perilously close to insoluble.

From "Founding Brothers: The Revolutionary Generation" by Joseph J. Ellis