inhibitor

Methanol helps prevent freezing and the accumulation of solid hydrates that can plug gas-compression equipment and limit pipeline flow, and it acts as a solvent and corrosion inhibitor.

To determine whether inhibiting this structural reshaping could restore treatment response, the team tested two experimental OPA1 inhibitors.

"In some human studies, the data suggest that the angiotensin receptor inhibitors may be more beneficial to cognitive health than other drugs that lower blood pressure," Dr. Iadecola said.

This early signal suggests that a blood test could eventually help identify patients who are more likely to develop neuropathy, opening the door to preventive steps -- potentially including IRE1α inhibitors -- before nerve damage sets in.

Drugs known as checkpoint inhibitors target PD1 and have already proven effective at reviving T cells in cancers such as melanoma.