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Definitions

hypothesize

[hahy-poth-uh-sahyz, hi-] / haɪˈpɒθ əˌsaɪz, hɪ- /
VERB
speculate
Synonyms
STRONG
brainstorm cerebrate cogitate conjecture consider contemplate deliberate dope excogitate figure guess guesstimate
WEAK
beat one's brains build castles in air call it call the turn chew over dope out figure out have a hunch hazard a
Antonyms
STRONG
discard disregard forget ignore neglect

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Based on this, the researchers hypothesize that genetic variation in ST6GAL1 could affect Paraprevotella levels and, in turn, susceptibility to viral infection.

From Science Daily • Dec. 23, 2025

"A lot of people hypothesize what they would have done, or whether they would have been able to take on the attacker," said Astrid.

From BBC • Nov. 6, 2025

However, I hypothesize that there are more than polls count.

From Slate • Jun. 15, 2024

Scientists hypothesize that this stretch of land was a Neotropical corridor.

From Science Daily • May 30, 2024

Why hypothesize the existence of vast, super-deadly pandemics that seem unlike anything else in the historical record?

From "1491" by Charles C. Mann

From Roget's 21st Century Thesaurus, Third Edition Copyright © 2013 by the Philip Lief Group.