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Definitions

degenerative

[dih-jen-er-uh-tiv, -uh-rey-tiv] / dɪˈdʒɛn ər ə tɪv, -əˌreɪ tɪv /


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

CTE is a degenerative brain disease that has been found in people exposed to repetitive head trauma; it can be diagnosed only after death.

From Los Angeles Times • Apr. 7, 2026

Petrou was diagnosed with retinitis pigmentosa, a degenerative disorder that leads to vision loss, at age 18.

From The Wall Street Journal • Mar. 12, 2026

Li, who suffers from a genetic degenerative condition that progressively weakens muscles, relies on a ventilator permanently connected to his windpipe to breathe, but grows celery with the help of his 62-year-old mother.

From Barron's • Jan. 29, 2026

Osteoarthritis is a degenerative joint disease that affects about one in five adults in the United States and generates an estimated $65 billion each year in direct health care costs.

From Science Daily • Jan. 20, 2026

Because these small amounts of pesticides are cumulatively stored and only slowly excreted, the threat of chronic poisoning and degenerative changes of the liver and other organs is very real.

From "Silent Spring" by Rachel Carson