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most fundamental

ADJECTIVE

basic, important

Synonyms

STRONGEST

central constitutional crucial elemental elementary essential indispensable integral intrinsic major necessary paramount principal radical significant structural theoretical underlying vital

STRONG

bottom cardinal first key organic original primary prime primitive requisite supporting

WEAK

axiological axiomatic basal bottom-line constitutive foundational grass-roots meat-and-potatoes primordial rudimentary substratal substrative sustaining underived

Antonyms

STRONGEST

accessory auxiliary extrinsic inessential insignificant learned least lesser minor needless nonessential secondary trivial unimportant unnecessary

WEAK

additional advanced extra subordinate

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

"DNA repair is one of the most fundamental processes in biology," said lead investigator Muralidhar L. Hegde, Ph.D., professor of neurosurgery at the Houston Methodist Research Institute's Center for Neuroregeneration.

From Science Daily • Mar. 15, 2026

On the most fundamental level, the demand for privacy is not about paranoia or fear.

From Salon • Feb. 20, 2026

The mattering instinct “implicates both the most fundamental law of the science of matter, the law of entropy,” as well as “the biological imperative to resist it.”

From The Wall Street Journal • Jan. 9, 2026

You don’t need a class in economics to know the most fundamental fact about prices: Any asset is only worth what you can get someone else to pay you for it.

From The Wall Street Journal • Dec. 19, 2025

And I really do not think that America, adolescent and cocksure, a stranger to suffering and travail, an enemy of passion and sacrifice, is ready to probe into its most fundamental beliefs.

From "Black Boy" by Richard Wright