down with

diseased feeble ill sickly weak

debilitated down enfeebled indisposed sick wasting

below par feeling awful rocky run down sick as a dog under the weather unwell

able fit healthy hearty sound strong well

happy

apprehensive conscious informed judicious knowledgeable observant

acquainted alive au courant awake conversant familiar grounded hep to hip to in on in the know in the picture knowing on the beam on to perceptive plugged in savvy sensible sentient tuned-in up on versed wise to with it witting

ignorant indifferent senseless thoughtless unaware uninformed unmindful

unfamiliar unknowledgeable unwitting

active affected attentive interested

caring implicated

in on mixed up privy to solicitous

disinterested

happy inattentive uncaring unconcerned undisturbed uninvolved unperturbed untroubled unworried

abreast acquainted knowledgeable practiced proficient skilled versed

alive apprehensive au courant au fait aware cognizant comprehending conscious cool hep hip informed into kept posted knowing learned on the beam perceptive percipient plugged in sensible sentient up up-to-date versant well-informed witting

ignorant inexperienced

afflicted ailing diseased infirm poorly woozy

down

a wreck below par bummed feeling awful feeling rotten feeling terrible got the bug indisposed laid low off one's feet on sick list out of sorts peaked queasy rotten run down running a temperature sick as a dog under the weather unhealthy unwell

healthy

good sound strong well

ailing confined down sick

below par feeling rotten got a bug ill infirm laid up on sick list out of action poorly sickly under the weather unwell

happy healthy

bent disposed inclined tending well willing