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Definitions

degenerative

[dih-jen-er-uh-tiv, -uh-rey-tiv] / dɪˈdʒɛn ər ə tɪv, -əˌreɪ tɪv /


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

In setting out Jonathan’s defense, one of the filing’s most striking assertions is that Isak suffered from bilateral gonarthrosis in both knees, a degenerative joint condition that causes cartilage wear, pain, stiffness and reduced mobility.

From The Wall Street Journal • May 28, 2026

The mustached southerner, yachting enthusiast and philanthropist, whose empire also included sports clubs, had been suffering from the degenerative disease Lewy Body Dementia.

From Barron's • May 6, 2026

Parkinson's disease, is a degenerative condition which affects how your brain communicates with the muscles in the body.

From BBC • Apr. 16, 2026

CTE is a degenerative brain disease that has been found in people exposed to repetitive head trauma; it can be diagnosed only after death.

From Los Angeles Times • Apr. 7, 2026

Dr. Darwin was now in a wheelchair, Bessy was stuck in a fog, and Josiah was sinking from either a stroke or a degenerative neurological disease.

From "Charles and Emma: The Darwins' Leap of Faith" by Deborah Heiligman



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