degeneration

The disease has several subtypes based on where the degeneration begins its advance through the brain.

But even grappling with macular degeneration, Oliphant refuses to look away.

One letter appears to show that Moth had previously been considered as having an "atypical form of corticobasal degeneration", but further examination suggested he may have "an even more unusual disorder, perhaps monogenetic".

"Look around you at these monstrosities of insanity, insolence, incompetence and degeneration," he declared in his opening address.

Her chief obstacle to more theatre work was her eyesight, she had macular degeneration, which made the stage increasingly difficult.