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Definitions

backbone

[bak-bohn] / ˈbækˌboʊn /


NOUN
spinal column of vertebrate
Synonyms


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

"They do a fantastic job for our health system, they are the unsung heroes, the backbone of our social care system and our health system, and they need our support."

From BBC • Mar. 31, 2026

Nvidia’s graphics processing units have been the backbone of AI development thus far, but central processing units are having a moment.

From MarketWatch • Mar. 25, 2026

Untangling the government’s stake is the critical issue for private shareholders in Fannie and Freddie, which buy mortgages from lenders and form the backbone of the U.S. housing market.

From Barron's • Mar. 20, 2026

Supplements went from a means of treating diseases caused by nutritional deficiencies in the 1900s to lifestyle products that are now the backbone of a $70 billion industry.

From The Wall Street Journal • Mar. 18, 2026

Only by the most special pleading could I imagine the polynucleotide backbone bending enough to accommodate irregular base sequences.

From "Double Helix" by James D. Watson