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Definitions

backbone

[bak-bohn] / ˈbækˌboʊn /


NOUN
spinal column of vertebrate
Synonyms


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Nvidia’s graphics processing units have been the backbone of AI development thus far, but central processing units are having a moment.

From MarketWatch • Mar. 25, 2026

“He has been the backbone of our family,” said Maria, 56.

From The Wall Street Journal • Mar. 23, 2026

"Bob had real backbone, on and off the screen," said Streisand.

From Barron's • Mar. 15, 2026

These bonds create the backbone of countless substances including fuels, plastics and complex biological molecules.

From Science Daily • Mar. 14, 2026

Francis’ grumbles did not disturb me, however, because further refining of our latest backbone without a solution to the bases would not represent a real step forward.

From "Double Helix" by James D. Watson