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Definitions

backbone

[bak-bohn] / ˈbækˌboʊn /


NOUN
spinal column of vertebrate
Synonyms


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

See Examples For:

RNA also appears to hold fewer water molecules around its backbone than DNA.

From Science Daily ● Oct. 2, 2026

They are the physical backbone of the internet.

From MarketWatch ● Sep. 18, 2026

Transfer pathways, he added, “will remain essential, and CSU and UC will always be the backbone of baccalaureate education in California.”

From Los Angeles Times ● Sep. 1, 2026

The U.S. has more than 5,400 data centers, which are the backbone of the internet and power the apps on your smartphone.

From The Wall Street Journal ● Aug. 31, 2026

So in building models we would postulate that the sugar-phosphate backbone was very regular, and the order of bases of necessity very irregular.

From "Double Helix" by James D. Watson

The chart shows strongly performing security and infrastructure, which provides “critical data backbones, compute pipelines and complex protection systems that generative models actively expand rather than displace.”

From MarketWatch ● Jul. 27, 2026

For decades, palaeontologists believed that the largest ocean predators were vertebrates with backbones such as fish and reptiles while invertebrates like octopuses and squid played supporting roles.

From BBC ● Apr. 23, 2026

Scientists at the University of St Andrews have identified an important missing piece in understanding how animals with backbones first evolved.

From Science Daily ● Feb. 4, 2026

Animals without a backbones evolved first, around 700 million years ago.

From The Wall Street Journal ● Nov. 21, 2025

The two sugar-phosphate backbones twist about on the outside with the flat hydrogen-bonded base pairs forming the core.

From "Double Helix" by James D. Watson




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