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Definitions

antagonist

[an-tag-uh-nist] / ænˈtæg ə nɪst /


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Neurocrine already markets Crenessity, an oral CRF1 receptor antagonist used to treat congenital adrenal hyperplasia, which is a collection of genetic disorders affecting the adrenal glands.

From MarketWatch • Apr. 6, 2026

Leavitt also leaned into her favorite antagonist — the press.

From Salon • Mar. 6, 2026

As in normal years, worshippers booed and waved noisemakers each time the story's antagonist, Haman, was announced, before drinking and dancing to pop music despite the unusual setting.

From Barron's • Mar. 2, 2026

In “The Mask,” also released in 1994, he played mobster Dorian Tyrell, antagonist to Jim Carrey’s Stanley Ipkiss, a.k.a. the Mask.

From Los Angeles Times • Feb. 19, 2026

Franklin regarded nature as an antagonist that would inevitably submit to force, good breeding, and Victorian discipline.

From "Into the Wild" by Jon Krakauer