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Definitions

antagonist

[an-tag-uh-nist] / ænˈtæg ə nɪst /


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Neurocrine already markets Crenessity, an oral CRF1 receptor antagonist used to treat congenital adrenal hyperplasia, which is a collection of genetic disorders affecting the adrenal glands.

From MarketWatch • Apr. 6, 2026

Leavitt also leaned into her favorite antagonist — the press.

From Salon • Mar. 6, 2026

As in normal years, worshippers booed and waved noisemakers each time the story's antagonist, Haman, was announced, before drinking and dancing to pop music despite the unusual setting.

From Barron's • Mar. 2, 2026

Jordan’s performance as complex antagonist Erik Killmonger in Coogler’s “Black Panther” drew widespread awards attention from critics groups, and the film’s cast won the SAG ensemble prize — Jordan’s highest acting honor to date.

From Los Angeles Times • Nov. 21, 2025

I trembled as I tore a cartridge with my teeth; but our antagonist and his friends, outnumbered and outflanked, were beating a retreat, ducked low, into an alley.

From "The Astonishing Life of Octavian Nothing, Traitor to the Nation, Volume II: The Kingdom on the Waves" by M.T. Anderson