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Definitions

antagonist

[an-tag-uh-nist] / ænˈtæg ə nɪst /


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

The road is looking similarly tough for Ed Gallrein, whom the president backs to take out his longtime antagonist, Kentucky Rep. Thomas Massie.

From The Wall Street Journal • Apr. 23, 2026

Neurocrine already markets Crenessity, an oral CRF1 receptor antagonist used to treat congenital adrenal hyperplasia, which is a collection of genetic disorders affecting the adrenal glands.

From MarketWatch • Apr. 6, 2026

Veteran video game actor Troy Baker is nominated twice - for his lead performance as Indiana Jones in The Great Circle and for his supporting role as antagonist Higgs in Death Stranding 2.

From BBC • Mar. 12, 2026

As in normal years, worshippers booed and waved noisemakers each time the story's antagonist, Haman, was announced, before drinking and dancing to pop music despite the unusual setting.

From Barron's • Mar. 2, 2026

One of the leading researchers in the field, who helped write the 2009 Amherst paper, is Daniel Anderson, a professor at UMass Amherst, and he’s anything but a purebred television antagonist.

From "A Deadly Wandering: A Mystery, a Landmark Investigation, and the Astonishing Science of Attention in the Digital Age" by Matt Richtel




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