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Definitions

antagonist

[an-tag-uh-nist] / ænˈtæg ə nɪst /


Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

Neurocrine already markets Crenessity, an oral CRF1 receptor antagonist used to treat congenital adrenal hyperplasia, which is a collection of genetic disorders affecting the adrenal glands.

From MarketWatch • Apr. 6, 2026

Leavitt also leaned into her favorite antagonist — the press.

From Salon • Mar. 6, 2026

As in normal years, worshippers booed and waved noisemakers each time the story's antagonist, Haman, was announced, before drinking and dancing to pop music despite the unusual setting.

From Barron's • Mar. 2, 2026

Vecna, the main antagonist from Season 4, had been seeking out four victims whose deaths would open four gates to the Upside Down.

From Los Angeles Times • Nov. 20, 2025

He liked that there was a new protagonist in the same world and that the previous protagonist was now the antagonist.

From "Healer of the Water Monster" by Brian Young




Vocabulary lists containing antagonist