substances

NOUN

entity, element

Synonyms

STRONGEST

item material object stuff texture

STRONG

actuality animal being body bulk concreteness core corpus fabric force hunk individual mass matter person phenomenon reality staple thing

WEAK

something

Antonyms

STRONG

abstract fantasy inanimate nothing nothingness plant

WEAK

poverty

NOUN

essence, meaning

Synonyms

STRONGEST

amount effect meat significance strength stuff subject

STRONG

ABCs basis body bottom burden center core corpus crux drift essentiality focus gist guts heart import innards kernel marrow mass matter nitty-gritty nub pith point purport quintessence sense soul staple tenor theme thrust upshot

WEAK

bottom line brass tacks general meaning gravamen name of the game nuts and bolts sum total virtuality way of it

Antonyms

STRONG

cowardice exterior exteriority fear insignificance nothing nothingness outside periphery surface

WEAK

poverty

NOUN

wealth

Synonyms

STRONG

affluence assets estate fortune means property resources riches worth

Antonyms

STRONG

debt

WEAK

poverty

Example Sentences

Examples are provided to illustrate real-world usage of words in context. Any opinions expressed do not reflect the views of Dictionary.com.

MLB spoke with Dodgers and Rams physician Neal ElAttrache about a New York Times story that connected him with UFC fighter Conor McGregor taking banned substances.

From Los Angeles Times • Jun. 24, 2026

Navsunli promises to replace a defective gene, allowing boys who take the drug to start producing a protein that prevents the buildup of harmful substances in the brain and tissues.

From The Wall Street Journal • Jun. 22, 2026

Diabetes can also weaken the brain’s protective barrier, letting harmful substances in.

From Science Daily • Jun. 17, 2026

The FDA advisory committee will consider whether to include the seven peptides on a list of drug substances that compounding pharmacies can make with a prescription.

From Barron's • Jun. 16, 2026

This quality is possessed by some chemicals of the chlorinated hydrocarbon group and by others of the organophosphorus group, all synthetically produced, as well as by certain naturally occurring substances.

From "Silent Spring" by Rachel Carson